Antioxidants and nitrate tolerance.
نویسندگان
چکیده
authors and five references. They should not have tables or figures and should relate solely to an article published in Circulation within the preceding 12 weeks. Only some letters will be published. Authors of those selected for publication will receive prepublication proofs, and authors of the article cited in the letter will be invited to reply. Replies must be signed by all authors listed in the original publication.
منابع مشابه
Effect of antioxidant treatments on nitrate tolerance development in normotensive and hypertensive rats.
OBJECTIVES To investigate the effect of chronic antioxidant treatments on the development of nitrate tolerance in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats by evaluating (i) coronary vascular reactivity, (ii) lipid peroxidation (malondialdehyde), and (iii) peroxynitrite formation (3-nitrotyrosine). METHODS Tolerance was induced in 16-week-old male SHR and WKY, ...
متن کاملEffects of Atorvastatin on Nitrate Tolerance in Diabetic Rats
Statins have been reported to show preventive effect on nitrate tolerance in normal rats, but there are no reports on their effect in diabetic animals. In this study, diabetes was induced in male wistar rats by a single intraperitoneal injection of streptozotocin (45 mg/kg). Five groups of diabetic and five groups of normal rats were treated; groups 1 (of normal and diabetic rats) received ator...
متن کاملEffects of Atorvastatin on Nitrate Tolerance in Diabetic Rats
Statins have been reported to show preventive effect on nitrate tolerance in normal rats, but there are no reports on their effect in diabetic animals. In this study, diabetes was induced in male wistar rats by a single intraperitoneal injection of streptozotocin (45 mg/kg). Five groups of diabetic and five groups of normal rats were treated; groups 1 (of normal and diabetic rats) received ator...
متن کاملEvaluation of low temperature tolerance indices in seedlings of Citrus aurantium under potassium nitrate nutrition.
In order to evaluate the effects of potassium nitrate nutrition on some low temperature tolerance indices in Citrus aurantium seedlings a factorial experiment was conducted based on a completely randomized design with four replications at the Institute of Citrus Research in Ramsar. Treatments were potassium nitrate nutrition at four levels (0, 2.5, 5, and 10 mM) and temperature at four levels (...
متن کاملEvaluation of possible effects of crocin against nitrate tolerance and endothelial dysfunction
Objective(s): One of the most important problems of taking nitroglycerin is the nitrate tolerance phenomenon and endothelial dysfunction. Oxidative stress is a high-emphasized one of tolerance mechanisms. The possible effect of crocin, one of the anti-oxidant ingredients of saffron, on the nitrate tolerance model was investigated.Materials and Methods: I...
متن کاملComplex I dysfunction and tolerance to nitroglycerin: an approach based on mitochondrial-targeted antioxidants.
Nitroglycerin (GTN) tolerance was induced in vivo (rats) and in vitro (rat and human vessels). Electrochemical detection revealed that the incubation dose of GTN (5x10(-6) mol/L) did not release NO or modify O(2) consumption when administered acutely. However, development of tolerance produced a decrease in both mitochondrial O(2) consumption and the K(m) for O(2) in animal and human vessels an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Circulation
دوره 98 13 شماره
صفحات -
تاریخ انتشار 1998